Our Technology:
Performance without compromise.

Why Lyophilized Growth Factors Fall Short

The protein structure of growth factors depend on a delicate hydration environment to maintain biological activity. When subjected to lyophilization, that environment is destroyed.

Strong urea breaks apart aggregates, followed by attempted refolding

Ice crystals crush and distort protein structures as ice expands

Lyophilization removes water causing unfolding and tangling into inactive aggregates

The result:

Reduced signaling activity

Increased lot-to-lot variability

Inconsistent experimental outcome

Even after reconstitution, these changes are not reversible, leaving only ~50–70% of lyophilized proteins are functionally active.

The Real Cost: Variability in Your Data.

The Real Cost:
Variability in Your Data.

Our NativFold™ Solution

Designed for biological performance, the NativFold Production Platform is engineered for preservation of native bioactivity from expression to application in the lab.

NativFold Platform preserves native structures for increased bioactivity

Protective Matrix shields proteins from damage during freeze-thaw

Our Always Hydrated approach produces growth factors in solution in the optimal environment

We support optimal protein folding and function to reduce aggregation and improve consistency in performance. No reconstitution. No variability between production and application.

Consistency you can design experiments around.

Our NativFold Growth Factors offer:

98% monomeric recovery
Reliable protein signaling
Reduced need for over-supplementation
Stable performance across experiments and lots

Our NativFold Growth Factors offer:

98% monomeric recovery
Reliable protein signaling
Reduced need for over-supplementation
Stable performance across experiments and lots

(256) 384-8823

contact@valorsci.com

Our Technology:Performance without compromise.

The protein structure of growth factors depend on a delicate hydration environment to maintain biological activity. When subjected to lyophilization, that environment is destroyed.

The protein structure of growth factors depend on a delicate hydration environment to maintain biological activity. When subjected to lyophilization, that environment is destroyed.

The result:

The result:

The result:

The Real Cost: Variability in Your Data.

The Real Cost: Variability in Your Data.

The Real Cost:Variability in Your Data.

We support optimal protein folding and function to reduce aggregation and improve consistency in performance. No reconstitution. No variability between production and application.

We support optimal protein folding and function to reduce aggregation and improve consistency in performance. No reconstitution. No variability between production and application.

Consistency you can design experiments around.

Consistency you can design experiments around.

Consistency you can design experiments around.

Our Technology:
Performance without compromise.

The Real Cost:
Variability in Your Data.